Nanopore Event-Transduction Signal Stabilization for Wide pH Range under Extreme Chaotrope Conditions
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چکیده
منابع مشابه
Nanopore Event-Transduction Signal Stabilization for Wide pH Range under Extreme Chaotrope Conditions.
Operation of an α-hemolysin nanopore transduction detector is found to be surprisingly robust over a critical range of pH (6-9), including physiological pH = 7.4 and polymerase chain reaction (PCR) pH = 8.4, and extreme chaotrope concentration, including 5 M urea. The engineered transducer molecule that is captured in the standard α-hemolysin nanopore detector, to transform it into a transducti...
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ژورنال
عنوان ژورنال: Molecules
سال: 2016
ISSN: 1420-3049
DOI: 10.3390/molecules21030346